TB has been marginalized for a very long time and progress on the disease has been hampered by a chronic lack of political will. Tuberculosis mostly affects adults in their most productive years. However, all age groups are at risk. Over 25% of cases and deaths are in the African region.

ACT aims to address the lack of political will through continuous and strategic advocacy efforts with key decision makers and players from global organizations such as the Global Fund, WHO, UN, ECOWAS, SADC, NEPAD and AU amongst others at regional and international level.
ACT aims to influence international and regional TB policy, complement public sector efforts and mobilize resources to eliminate TB. 

ACT members regularly contribute to public consultations on the fight against TB in Africa, actively participate in relevant AU and WHO forums and stand available to provide information and advice to policy-makers on issues that the network has particular expertise.